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Ketamine treatment for optimal mental health.

Provides hope when traditional therapies have failed

Understanding the Science of Ketamine

How Ketamine Works

Ketamine is what is known as an N-methyl-D-aspartate (NMDA) receptor antagonist. NMDA receptors play a major role in depression. Ketamine infusion therapy works by encouraging and supporting neuron growth and restoring electrical activity in certain neurons that no longer work in the brain.Lopez, J.P.; Lucken, M.D.; Brivio, E.; et. al.; Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2. Neuron. 2022 May 25;S0896-6273(22)00409-3. doi: 10.1016/j.neuron.2022.05.001.

The Science of Ketamine Infusions

Better known as a medication for general anesthesia, ketamine has been used safely with adults, adolecents, and children in operating rooms around the world for more than 50 years.  

A compelling amount of evidence suggests when taken for mental health treatment in sub-anaesthetic doses, ketamine infusions can restore the damaged brain pathways that cause mood disorders. Patients suffering from depression, anxiety, PTSD, postpartum depression, fibromyalgia, OCD, substance abuse, addiction, or pain now have an alternative treatment option available.

Speed

It can take several weeks for traditional antidepressants to take effect. Ketamine works within hours to start proving you with much needed relief.

Success

Ketamine has been shown to be effective for many who struggle to find relief with traditional antidepressants. Roughly one-third of patients will respond to their first oral antidepressant leaving  two-thirds of patients who will need to find another option. A change in the class of antidepressant will sometimes work for the patient. This is why each patient’s care is tailored to his or her needs.

Side Effects

Traditional antidepressants can cause many side effects, including weight gain, sexual dysfunction, headaches, nausea, and restlessness. Ketamine treatment does not have any lasting side effects.

Our team has delivered 6,000 + treatments for:

Click on each condition to learn more.

“I am so much better than I was before, and the greatest gift Ketamine has given me is hope. I adore the staff there more than you can imagine…Ketamine Wellness Clinic saved my life.”

Why Ketamine

“Recent data suggest that ketamine, given intravenously, might be the most important breakthrough in antidepressant treatment in decades.”

Thomas Insel, Director National Institute of Mental Health (2002–2015)

Used Safely 50+ Years

Decades of clinical use proves it to be safe and effective.

Rapid Relief

Ketamine produces profound and rapid antidepressant effects in one to four hours.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225830/

SSRIs vs. Ketamine

Ketamine works differently than traditional antidepressants and is often effective when SSRIs fail.

Strengthen Your Mindfulness

Psychedelics have the power to shape us in a profound & positive way and heal us through understanding and insight.​

Depression

Depression is a mood disorder that causes a persistent feeling of sadness, emptiness or hopelessness. There are various forms of depression: major depression, clinical depression, postpartum depression, manic depression. All lead to behavioral or physical symptoms.

Symptoms of Depression

  • Loss of interest in once pleasurable activities
  • Changes in sleep, e.g., insomnia, or oversleeping
  • Restlessness, anxiety, easily agitated
  • Lack of energy or fatigue
  • Change in weight – weight loss, reduced appetite or weight gain, increased cravings
  • Feelings of worthlessness, guilt, or blame
  • Trouble concentrating, loss of memory, indecisiveness

General Anxiety Disorder

General Anxiety Disorder is an excessive, ongoing anxiety and worry about everyday routine events. Daily life becomes a constant state of worry, fear or dread. The worry is often unrealistic or exaggerated and dominates the person’s thoughts and behavior.

Symptoms of General Anxiety Disorder

  • Uncontrollable, excessive, ongoing worry and tension
  • Difficulty sleeping
  • Expecting the worst
  • Inability to relax
  • Easily irritated
  • Difficulty concentrating, mind goes blank

Bipolar Disorder

Bipolar Disorder is a mood disorder, also known as manic-depressive disorder. People with this disorder experience extreme mood swings from deep depression to extreme energized behavior (known as manic episodes).

Symptoms of Bipolar Disorder

  • Increased talkativeness
  • Racing thoughts, poor attention
  • Increased risk taking (risky sexual behavior, spending money, etc.)
  • Changes in sleep patterns and eating habits
  • Deep depression
  • Lack of energy and motivation
  • Feeling worthless, guilt
  • Suicidal thoughts

Post-Traumatic Stress Disorder (PTSD)

Post-Traumatic Stress Disorder can occur in people who have experienced or witnessed a traumatic or terrifying event. PTSD causes flashbacks or uncontrollable thoughts of the traumatic event, nightmares, and severe anxiety.

Symptoms of Post-Traumatic Stress Disorder (PTSD)

  • Repeatedly reliving the event or trauma
  • Avoiding reminders of the trauma, e.g. places, events, objects
  • Panic attacks when thinking of event
  • Being constantly on guard, paranoia, mistrust
  • Detachment from family and friends
  • Difficulty sleeping, concentrating, irritability, angry outbursts, aggressive behavior
  • Overwhelming guilt or shame

Suicidal Ideation

Suicidal Ideation is defined by having a preoccupation with suicidal thoughts. These thoughts can be intensified when accompanied by mental illness such as depression or bipolar disorder. Active suicidal ideation involves not only a wish to die but also a plan of action to carry out the suicide. Passive suicidal ideation involves a desire to die with no specific plan.

Symptoms of Suicidal Ideation

  • Withdrawing from others, avoiding social contact
  • Speaking about death, dying
  • Increased risky behaviors including drugs and alcohol abuse
  • Belief that suicide is the only remedy to end emotional pain
  • Feeling hopeless, self-loathing
  • Changes in sleeping or eating habits
  • Severe anxiety or agitation

Obsessive Compulsive Disorder (OCD)

Obsessive Compulsive Disorder is an anxiety disorder characterized by unwanted repeated thoughts, urges, and mental images that cause one to engage in ritualized, repeated behaviors. Some individuals may also experience a tic disorder—repeated, sudden muscle movements including sounds.

Symptoms of Obsessive Compulsive Disorder (OCD)

  • Obsessive hand washing, fear of germs and contamination
  • Repeatedly checking on things
  • Having things symmetrical or in perfect order
  • Aggressive thoughts towards others or self
  • Unwanted, forbidden or taboo thoughts involving sex, religion, or harm
  • Compulsive counting

Addiction + Substance Use Disorder

Addiction and Substance use disorder (SUD) is a condition in which there is uncontrolled use of a substance. Substances can include such things as alcohol, tobacco, prescription, or illicit drugs. Persons with SUD have an intense focus on a substance(s) to the point where it affects a person’s ability to function in daily activities. People keep using the substance even when they know it is causing or will cause problems. The most severe SUDs are sometimes called addictions.

Signs of Addiction/Substance Use Disorder (SUD)

  • Having an intense urge for a substance(s) and feeling like you need more of it
  • Needing more of the substance(s) in order to get the same effect
  • Inability to stop taking the substance(s) on your own
  • Engaging in risky activities or doing things you wouldn’t normally do when you are under the influence of the substance(s)
  • Experiencing withdrawal symptoms if you try to stop taking the substance(s)
  • Problems at school or work — not meeting obligations because of the substance(s) use
  • Using the drug despite knowing it harms you physically or mentally, or causes issues in your life

Postpartum Depression

Some moms experience “baby blues,” which can happen during or after pregnancy and usually lasts a couple of days to a couple of weeks. However, there is a more severe and longer-lasting mood condition called, postpartum depression. Postpartum depression can cause persistent feelings of sadness, emptiness, hopelessness, crying, paranoia, as well as guilt, or anxiety. Postpartum depression should be taken very seriously.

Symptoms of Postpartum Depression

  • Restlessness, anxiety, easily agitated
  • Excessive crying
  • Insomnia or oversleeping
  • Feelings of hopelessness
  • Feelings of worthlessness, guilt, or blame
  • Lack of interest in your baby
  • Thoughts of harming yourself or your baby

Migraines / Headaches

A migraine is an intense, throbbing headache that usually affects one side of the head. Migraines are often triggered by environment, stress, hormones, and many other factors. Migraines occur most frequently in women and affect day to day activity.

Symptoms of Migraines / Headaches

  • Pounding, throbbing pain affecting the whole head or shifting from side to side
  • Blurred vision
  • Nausea, vomiting, abdominal pain
  • Fatigue, dizziness
  • Loss of appetite

Neuropathic Pain

Neuropathic pain is a chronic condition that leads to persistent, intense pain that can fluctuate throughout the day. Often due to injury or disease, the nerves involved within the sensory system send altered signals to other pain centers, including the brain and spinal cord. This disrupted communication can lead to sensations of numbness and pain.

Symptoms of Neuropathic Pain

  • Shooting, burning, intense pain
  • Tingling and numbness or “pins and needles” feeling
  • Evoked pain caused by normal activities such as cold weather, or touch
  • Spontaneous pain with no source or trigger

Complex Regional Pain Syndrome

A chronic pain condition that usually affects one limb and is most often caused by an injury. This pain is characterized as out of proportion to the original injury.

Symptoms of Complex Regional Pain Syndrome (CRPS)

  • Injured limb has intense throbbing or burning pain
  • Moving or touching the affected limb is often intolerable
  • Changes in skin temperature, color, or texture
  • Muscle spasms, local swelling, joint tenderness
  • Pain may involve or spread to other areas of the body

Fibromyalgia

Fibromyalgia is a musculoskeletal disorder that intensifies the way the brain processes pain, resulting in hypersensitive pain receptors. The results are widespread pain, fatigue, discomfort and “fibro fog” which impairs the ability to focus or pay attention.

Symptoms of Fibromyalgia

  • Widespread constant pain throughout the entire body
  • Fatigue, waking up tired, sleep disrupted by pain
  • Trouble focusing (“fibro fog”), difficulty concentrating
  • Depression or anxiety

Iris Mejia, RN

Iris Mejia, RN, is a registered nurse with a bachelor’s degree in nursing from the University of Hawaii Maui College. With 21 years of experience as a Labor and Delivery nurse, she developed a keen interest in mental health nursing. Her firsthand experience with ketamine infusion therapy led her to pursue her passion in this field.

Iris is dedicated to helping patients achieve their optimal well-being through compassionate care and evidence-based practices.

Outside of work, Iris enjoys practicing yoga, traveling, and spending quality time with her family.

Susan DeRobertis,
BSN, BSN, PMHRN-BC

Susan DeRobertis, BSN, BSN, PMHRN-BC, is a board-certified Psychiatric Mental Health Registered Nurse and holds a Bachelor of Science in Nursing from Cal State Fullerton.

Susan’s commitment to mental health and wellness is driven by a deep understanding of the challenges faced by those struggling with mood disorders. Having witnessed firsthand the limitations of traditional therapies for depression, anxiety, PTSD, and other mood and chronic pain disorders, she is an advocate of ketamine infusion therapy as a transformative treatment option. Susan is passionate about supporting individuals and their families through their mental health journeys and continues to be excited when she sees firsthand the positive changes that ketamine therapy can bring.

Over the past decade, Susan has dedicated herself to providing care at the Mental Health and Wellness Institute at Mission Hospital Laguna Beach. She is also a nursing instructor at the University of California, Irvine.

Beyond her professional accomplishments, Susan is a devoted mother, a talented musician, and an avid live music fan. She finds joy in spending quality time with her daughters, traveling, and attending concerts.