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Ketamine at Home: Why the Standards Can't Travel With It

The American Society of Anesthesiologists recently raised formal concerns about the boom in at-home ketamine delivery. Their concerns center specifically on at-home delivery and telehealth prescribing without adequate supervision — patients receiving a powerful anesthetic at home, with no one present to monitor their breathing, blood pressure, or response to the medication.

It’s worth remembering that ketamine is, first and foremost, an anesthetic — one that’s been used in operating rooms for decades under strict protocols. Its role in helping patients with treatment-resistant depression, PTSD, and chronic anxiety is now well-established in literature. But the drug itself hasn’t changed. And neither should the standards for how it’s administered.

That’s why at Ketamine Wellness Clinic of Orange County, our standards of patient safety, monitoring, and physician oversight have always reflected the clinical guidelines established by the ASA and the Medical Board of California.

Bioavailability: Precision Dosed for Full Absorption

IV ketamine delivers 100% bioavailability — what we administer is exactly what your patient receives, with real-time dosing control that oral formulations simply can’t come close to matching. For patients with treatment-resistant depression or PTSD, that consistency is what makes the difference between adequate treatment and optimal treatment.

Physician-Monitored, Every Infusion

Every patient at our clinic is monitored continuously throughout their infusion — vital signs, oxygen levels, and clinical response — with a physician and clinical staff present and able to intervene immediately.

The Evidence Was Built on IV Administration

The robust clinical evidence supporting ketamine’s antidepressant effects was established through IV administration. Only IV administration offers the precise dosing needed to achieve optimal therapeutic effect. The therapeutic setting, the clinical relationship, and the quality of the experience itself all contribute to outcomes in ways that a telehealth prescription and a home delivery cannot replicate.

We communicate with referring clinicians, follow your patient’s progress, and operate with the same standard of care you would expect from any supervised medical procedure — because that’s exactly what it is.

As the at-home ketamine space continues to aggressively market to patients through social media advertising, and regulators work to catch up, we remain committed to the standard this medication has always deserved..

Read the ASA’s full statement here. 

Iris Mejia, RN

Iris Mejia, RN, is a registered nurse with a bachelor’s degree in nursing from the University of Hawaii Maui College. With 21 years of experience as a Labor and Delivery nurse, she developed a keen interest in mental health nursing. Her firsthand experience with ketamine infusion therapy led her to pursue her passion in this field.

Iris is dedicated to helping patients achieve their optimal well-being through compassionate care and evidence-based practices.

Outside of work, Iris enjoys practicing yoga, traveling, and spending quality time with her family.

Susan DeRobertis,
BSN, PMHRN-BC

Susan DeRobertis, BSN, PMHRN-BC, is a board-certified Psychiatric Mental Health Registered Nurse and holds a Bachelor of Science in Nursing from Cal State Fullerton.

Susan’s commitment to mental health and wellness is driven by a deep understanding of the challenges faced by those struggling with mood disorders. Having witnessed firsthand the limitations of traditional therapies for depression, anxiety, PTSD, and other mood and chronic pain disorders, she is an advocate of ketamine infusion therapy as a transformative treatment option. Susan is passionate about supporting individuals and their families through their mental health journeys and continues to be excited when she sees firsthand the positive changes that ketamine therapy can bring.

Over the past decade, Susan has dedicated herself to providing care at the Mental Health and Wellness Institute at Mission Hospital Laguna Beach. She is also a nursing instructor at the University of California, Irvine.

Beyond her professional accomplishments, Susan is a devoted mother, a talented musician, and an avid live music fan. She finds joy in spending quality time with her daughters, traveling, and attending concerts.