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Ketamine shows promise in the treatment of addiction and substance abuse due to its unique pharmacological properties and potential to enhance therapeutic outcomes.
Ketamine works primarily as an NMDA (N-methyl-D-aspartate) receptor antagonist. This receptor is part of the glutamate system, which plays a key role in learning, memory, and mood regulation. By inhibiting this receptor, ketamine infusions may weaken or even eliminate triggers linked to alcohol and drug use. This mechanism makes ketamine treatments a promising alternative, especially given the complex interplay of environmental factors that often contribute to substance abuse.1
Studies suggest ketamine can reduce cravings and self-administration behaviors, as demonstrated in cases of alcohol, cocaine, and opioid (such as heroin) dependence. Furthermore, its rapid antidepressant effects can address co-occurring depression, which is a common trigger for relapse. Dissociative experiences induced by ketamine may provide profound psychological insights, further aiding recovery.2
As research into ketamine’s role in addiction treatment continues to unfold, its potential to revolutionize how we approach substance abuse becomes increasingly clear. By targeting both the neurological and psychological aspects of addiction, ketamine offers a beacon of hope for those struggling to break free from the cycle of dependence. For individuals seeking lasting recovery, ketamine may not only provide a pathway to healing but also a new beginning.
1.2 018. Jaffee. Psychology Today. Is Medication Assisted Treatment Good or Bad Research shows that pharmacotherapy helps improve quality of life. https://www.psychologytoday.com/us/blog/all-about-addiction/201810/is-medication-assisted-treatment-good-or-bad
2. 2018. Ezquerra-Romano, I., Lawn, W., Krupitsky, E., Morgan, CJA. Ketamine for the treatment of addiction: Evidence and potential mechanisms. https://www.sciencedirect.com/science/article/abs/pii/S0028390818300170?via%3Dihub
Iris Mejia, RN, is a registered nurse with a bachelor’s degree in nursing from the University of Hawaii Maui College. With 21 years of experience as a Labor and Delivery nurse, she developed a keen interest in mental health nursing. Her firsthand experience with ketamine infusion therapy led her to pursue her passion in this field.
Iris is dedicated to helping patients achieve their optimal well-being through compassionate care and evidence-based practices.
Outside of work, Iris enjoys practicing yoga, traveling, and spending quality time with her family.
Susan DeRobertis, BSN, BSN, PMHRN-BC, is a board-certified Psychiatric Mental Health Registered Nurse and holds a Bachelor of Science in Nursing from Cal State Fullerton.
Susan’s commitment to mental health and wellness is driven by a deep understanding of the challenges faced by those struggling with mood disorders. Having witnessed firsthand the limitations of traditional therapies for depression, anxiety, PTSD, and other mood and chronic pain disorders, she is an advocate of ketamine infusion therapy as a transformative treatment option. Susan is passionate about supporting individuals and their families through their mental health journeys and continues to be excited when she sees firsthand the positive changes that ketamine therapy can bring.
Over the past decade, Susan has dedicated herself to providing care at the Mental Health and Wellness Institute at Mission Hospital Laguna Beach. She is also a nursing instructor at the University of California, Irvine.
Beyond her professional accomplishments, Susan is a devoted mother, a talented musician, and an avid live music fan. She finds joy in spending quality time with her daughters, traveling, and attending concerts.
