Phone: (949)392-0159

Superiority of Ketamine IV Infusion Versus Ketamine Oral or Nasal

At Ketamine Wellness Clinic of Orange County, we believe in optimally treating your condition in order to ensure the best response to ketamine therapy.

When ketamine is given via IV infusion, 100% of the medicine is available to your brain and body and it is absorbed rapidly. Ketamine pills have been shown to have a very low absorption rate – only 17%. This means that your body is not absorbing and seeing the medical benefits of the full dose.

However, both intranasal and oral ketamine are not circulated directly into the bloodstream at the time of administration resulting in patients only seeing a fraction of the effect of the dose of ketamine administered. For example, with oral therapy the medication needs to go through both the stomach and liver, leaving only a small percentage of the drug to reach the brain.

The bioavailability of ketamine when administered intravenously is 100%. Our physicians are able to deliver a very precise dose to patients knowing that 100% of the medication will be made available to the patient’s brain for therapy.

This is why the physicians at Ketamine Wellness Clinic of Orange County believe so strongly in providing patients the option of ketamine therapy via IV. It gives the patient the best chance to have the maximum benefits of ketamine therapy.

Take the first step today.

Iris Mejia, RN

Iris Mejia, RN, is a registered nurse with a bachelor’s degree in nursing from the University of Hawaii Maui College. With 21 years of experience as a Labor and Delivery nurse, she developed a keen interest in mental health nursing. Her firsthand experience with ketamine infusion therapy led her to pursue her passion in this field.

Iris is dedicated to helping patients achieve their optimal well-being through compassionate care and evidence-based practices.

Outside of work, Iris enjoys practicing yoga, traveling, and spending quality time with her family.

Susan DeRobertis,
BSN, BSN, PMHRN-BC

Susan DeRobertis, BSN, BSN, PMHRN-BC, is a board-certified Psychiatric Mental Health Registered Nurse and holds a Bachelor of Science in Nursing from Cal State Fullerton.

Susan’s commitment to mental health and wellness is driven by a deep understanding of the challenges faced by those struggling with mood disorders. Having witnessed firsthand the limitations of traditional therapies for depression, anxiety, PTSD, and other mood and chronic pain disorders, she is an advocate of ketamine infusion therapy as a transformative treatment option. Susan is passionate about supporting individuals and their families through their mental health journeys and continues to be excited when she sees firsthand the positive changes that ketamine therapy can bring.

Over the past decade, Susan has dedicated herself to providing care at the Mental Health and Wellness Institute at Mission Hospital Laguna Beach. She is also a nursing instructor at the University of California, Irvine.

Beyond her professional accomplishments, Susan is a devoted mother, a talented musician, and an avid live music fan. She finds joy in spending quality time with her daughters, traveling, and attending concerts.